NHS codeine ‘side effect’ warning for 1 in 100 people

In 2024, over 74 million controlled drugs were prescribed in England alone, with more than 25 million of these being Schedule 5 drugs, including codeine, according to data from the Care Quality Commission. Codeine, a commonly prescribed painkiller, is classified as an opioid drug.

It targets the opioid receptors in the brain and other organs to produce effects similar to morphine, primarily providing significant pain relief. The NHS often prescribes codeine for pain management following surgery or injury, or when other painkillers such as paracetamol and ibuprofen are ineffective.

Typically, codeine is dispensed via prescription and can be taken as a tablet, liquid, or injection. However, lower-strength codeine can also be purchased from a pharmacy, usually combined with paracetamol as co-codamol or with ibuprofen, as in Nurofen Plus.

Despite its effectiveness as a pain reliever, codeine can have several side effects. The NHS warns that more than one in 100 people could experience symptoms such as constipation, nausea, confusion, fatigue, dizziness, and headaches, particularly when taken for extended periods.

The NHS website states: “Like all medicines, codeine can cause side effects in some people. But many people have no side effects or only minor ones. The higher the dose of codeine the more chance that you will get side effects.”

Nevertheless, some individuals may encounter more serious adverse reactions. Based on NHS data, fewer than one in 100 people might develop symptoms including muscle rigidity and signs linked to low blood pressure, such as dizziness or fatigue.

Common side effects associated with codeine

The length of time you require codeine will differ considerably depending on your need for pain management. In certain instances, you might only require codeine for several days, making you less prone to developing any symptoms.

Alternatively, you may require it for an extended period, though bear in mind that an alternative medication could be prescribed, particularly for chronic pain. NHS guidance emphasises this is especially true if you start experiencing adverse effects like constipation.

Managing constipation whilst taking codeine

Whilst constipation may be bothersome, it will probably only be short-lived, particularly if it’s connected to codeine usage. The NHS recommends people attempt to increase their fibre intake, which can help with bowel movements.

It is typically advised that adults consume between 18g and 21g of fibre daily.

  • Plain wholewheat biscuits
  • Whole grain cereals
  • Oats (especially porridge)
  • Wholemeal breads
  • Wholewheat pasta
  • Bulgur wheat
  • Brown rice
  • Potatoes with skin on
  • Beans
  • Lentils
  • Chickpeas
  • Most vegetables
  • Fresh or dried fruit
  • Rye crackers
  • Unsalted nuts or seeds
  • Oatcakes

Further guidance on taking codeine can be found on the NHS website here. You can also receive further guidance on geting more fibre into your diet here.

You May Also Like